Abstract

Among cutaneous propionibacteria, synthesis of neuraminidase is highest in strains of the species P. acnes. In the present study, neuraminidase activity was discovered in 90.0% of P. acnes strains isolated from acne lesions compared with 72.7% of strains from normal human skin. Neuraminidase-positive strains from acne lesions, moreover, produced statistically significant higher amounts of the enzyme ({ie1} = 727 mU/ml bacterial suspension) than isolates from normal skin ({ie1} = 392 mU/ml). Whereas the moderate production of neuraminidase by strains from patients with seborrheic eczema is probably of no causative importance, the enzyme has to be discussed as a potential etiologic factor in acne vulgaris.

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