Abstract
Background. Deep brain stimulation (DBS) of globus pallidus internus (GPi) has been used to treat primary dystonia for many years. However, patients respond differently to DBS. Some patients could not benefit much from it. Classification of local field potential (LFP) neural state in GPi may provide a new method to identify the differences in neuropathophysiological mechanisms, which may predict DBS outcome and investigate neurobiological marker of dystonia for adaptive-DBS.
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