Abstract
Neural Plasticity in Obesity and Psychiatric Disorders.
Highlights
The review article entitled “Obesity Reduces Cognitive and Motor Functions across the Lifespan” by C
Lee et al expanded the field of knowledge in this area by showing novel associations between major depression and disruptive behaviors and single-nucleotide polymorphisms (SNPs) located within the genes encoding NMDA receptors (NMDAr)
The authors recruited 832 adolescents to evaluate their emotional and social impairments and to investigate their possible association with 59 SNPs harbored in NMDAr genes
Summary
The review article entitled “Obesity Reduces Cognitive and Motor Functions across the Lifespan” by C. The brain plasticity changes associated with obesity or psychiatric conditions could potentially expand the knowledge of both fields. The authors discuss the deleterious effects obesity-related brain plasticity and the central actions of leptin, BDNF, and IGF-1.
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