Abstract
Neural Plasticity and Neurogenesis in Mental Disorders.
Highlights
Despite the fact that adult neurogenesis is confined to very discrete regions of the brain, and the established role of adult neurogenesis in major depression notwithstanding, it is becoming increasingly apparent that the deregulation of neurogenesis may impact a much wider range of mental disorders
In this special issue on neural plasticity and neurogenesis in mental disorders, we are pleased to present a series of articles that reflect the broad scope of psychiatric and neurological conditions that are potentially impacted by abnormalities in neurogenesis and neuroplasticity
Varela-Nallar et al (“Andrographolide Stimulates Neurogenesis in the Adult Hippocampus”) report new data in this issue demonstrating the effects of Andrographolide (ANDRO) on adult hippocampal neurogenesis, a compound the authors have previously identified as a GSK3beta inhibitor
Summary
Despite the fact that adult neurogenesis is confined to very discrete regions of the brain, and the established role of adult neurogenesis in major depression notwithstanding, it is becoming increasingly apparent that the deregulation of neurogenesis may impact a much wider range of mental disorders. Editorial Neural Plasticity and Neurogenesis in Mental Disorders The continuous generation of newborn neurons in discrete regions of the brain throughout life, is widely regarded as a fundamental mechanism of neural plasticity.
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