Abstract
In this article, Ida Gerendai and Béla Halász describe the elegant studies from which they have derived the evidence for the existence and pathways of efferent and afferent neural connections between the ovary and hypothalamus, and the role which these pathways have to play in gonadal-hypothalamic feedback. The model which they have used concerns the effects of compensatory ovarian hypertrophy following hemiovariectomy. For the neuroendocrinologist, the involvement of possible neural pathways in areas previously considered to be only under a humoral control, has many far-reaching implications, and may provide explanations for a number of previously inexplicable observations.
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