Neural overlap between memory and social cognition during resting state

Abstract

Event Abstract Back to Event Neural overlap between memory and social cognition during resting state Raymond A. Mar1* and R. Nathan Spreng2 1 York University, Canada 2 Harvard University, United States Remembering events from the personal past (autobiographical memory) and inferring the thoughts and feelings of other people (mentalizing) share a neural substrate. The shared functional neuroanatomy of these processes has been demonstrated in a meta-analysis of independent task domains (Spreng et al., 2009) and within subjects performing both tasks (Rabin et al., 2010; Spreng & Grady, 2010). Here, we examine spontaneous low-frequency fluctuations in fMRI BOLD signal during rest from two separate regions key to memory and mentalizing, the left hippocampus and right temporal parietal junction, respectively. Activity in these two regions was then correlated with the entire brain in a resting-state functional connectivity analysis. Although the left hippocampus and right temporal parietal junction were not correlated with each other, both were correlated with a shared distributed network of brain regions. These regions were consistent with the previously observed overlap between autobiographical memory and mentalizing evoked brain activity found in past studies. Reliable patterns of overlap included the superior temporal sulcus, anterior temporal lobe, lateral inferior parietal cortex (angular gyrus), posterior cingulate cortex, dorsomedial and ventral prefrontal cortex, inferior frontal gyrus, and the amygdala. We propose that the functional overlap facilitates the integration of personal and interpersonal information and provides a means for personal experiences to become social conceptual knowledge. Funding: Supported by NIH Grant MH060941. Keywords: emotion, resting state Conference: XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011. Presentation Type: Poster Presentation Topic: Poster Sessions: Emotion, Motivation and the Social Brain Citation: Mar RA and Spreng R (2011). Neural overlap between memory and social cognition during resting state. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). doi: 10.3389/conf.fnhum.2011.207.00162 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 18 Nov 2011; Published Online: 28 Nov 2011. * Correspondence: Dr. Raymond A Mar, York University, Toronto, Canada, mar@yorku.ca Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Raymond A Mar R. Nathan Spreng Google Raymond A Mar R. Nathan Spreng Google Scholar Raymond A Mar R. Nathan Spreng PubMed Raymond A Mar R. Nathan Spreng Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.