Abstract
Mesodermal and spinal cord progenitors originate from common founder cells from which they segregate during development. Moreover, neural and mesodermal tissues closely interact during embryogenesis to ensure timely patterning and differentiation of both head and trunk structures. For instance, the fate and morphogenesis of neural progenitors is dependent on signals produced by mesodermal cells and vice-versa. While some of the cellular and molecular signals that mediate these interactions have been described, much more remains to be uncovered. The scope of this collection will cover these interactions between neural (CNS or PNS) and mesodermal progenitors in patterning body plans and specific body systems in vertebrate embryos. This includes, but is not limited to, interactions influencing the formation of body axes, neural tube formation, neural crest migration, gut development, muscle patterning and myogenesis.
Highlights
Mesodermal and spinal cord progenitors originate from common founder cells from which they segregate during development
This article is included in the Neural-mesodermal progenitor interactions in pattern formation collection
Editorial Clonal analysis indicated that trunk neural and mesodermal progenitors share a common lineage at an early developmental stage (Tzouanacou et al, 2009)
Summary
Mesodermal and spinal cord progenitors originate from common founder cells from which they segregate during development. This article is an Editorial and has not been subject to external peer review. Any comments on the article can be found at the end of the article.
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