Abstract
Reduction in gastric tone can occur before food reaches the stomach. That facilitates the reservoir function of the stomach. Mechanical stimulation of the pharynx and esophagus by swallowed food itself has been assumed to induce such a gastric response. However, the relationship between the gastric reservoir function and the oropharyngeal chemoreceptor has not been clarified. The present study aimed to demonstrate that chemoreceptive afferents in the superior laryngeal nerve (SLN) facilitate the reservoir function of the stomach in rats. Furthermore, the gastric response found in rats was demonstrated to be useful to facilitate reservoir function during fluid intake in humans using an electrogastrography (EGG) method. Gastric motor response induced by superior
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