Abstract
Neural circuits: Japan.
Highlights
This Frontiers Research Topic on “Neural Circuits: Japan” explores the diversity of innovative neural circuit research occurring across Japan
The cerebellum as well as the basal ganglia may be involved in its pathogenesis
These results suggest the involvement of the olivo-cerebellar pathway in dystonia (Hisatsune et al, 2013)
Summary
This Frontiers Research Topic on “Neural Circuits: Japan” explores the diversity of innovative neural circuit research occurring across Japan. One area of interest includes cerebellar local and efferent circuits, as well as mechanisms underlying synaptic plasticity in Purkinje cells, which have been a focus of intensive investigation by many Japanese researchers. In mice without Cbln1, delay eye blink conditioning, as well as LTD at the parallel fiber to Purkinje cell synapse, were impaired, even as previously formed conditioning responses were retained, suggesting a necessity for LTD selectively in conditioning formation (Emi et al, 2013).
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