Network analysis of trauma in patients with early-stage psychosis

Fatima Zahra Rami,Ling Li,Thong Ba Nguyen,Eui Tae Kim,Je-Chun Yu,Shi Hyun Kang,Young-Chul Chung,Sung-Wan Kim,Seung-Hee Won,Jung Jin Kim,Seung-Hwan Lee,Bong Ju Lee,Jing Sui,Bomi Lee,Kyu Young Lee,Je-Yeon Yun,Seung-Hyun Kim,Woo-Sung Kim,Yan Hong Piao

doi:10.1038/s41598-021-01574-y

Abstract

Childhood trauma (ChT) is a risk factor for psychosis. Negative lifestyle factors such as rumination, negative schemas, and poor diet and exercise are common in psychosis. The present study aimed to perform a network analysis of interactions between ChT and negative lifestyle in patients and controls. We used data of patients with early-stage psychosis (n = 500) and healthy controls (n = 202). Networks were constructed using 12 nodes from five scales: the Brief Core Schema Scale (BCSS), Brooding Scale (BS), Dietary Habits Questionnaire, Physical Activity Rating, and Early Trauma Inventory Self Report-Short Form (ETI). Graph metrics were calculated. The nodes with the highest predictability and expected influence in both patients and controls were cognitive and emotional components of the BS and emotional abuse of the ETI. The emotional abuse was a mediator in the shortest pathway connecting the ETI and negative lifestyle for both groups. The negative others and negative self of the BCSS mediated emotional abuse to other BCSS or BS for patients and controls, respectively. Our findings suggest that rumination and emotional abuse were central symptoms in both groups and that negative others and negative self played important mediating roles for patients and controls, respectively.Trial Registration: ClinicalTrials.gov identifier: CUH201411002.

Highlights

Childhood trauma (ChT) is a risk factor for psychosis
In a non-clinical population, individuals with adverse childhood experiences were at increased risk of poor health outcomes such as physical inactivity, overweight or obesity, and diabetes[21]. These findings suggest that in individuas with psychosis, ChT is associated with rumination, negative schemas, poor diet, and reduced physical activity, which can be grouped as a “negative life style”
The scores on the negative self and negative others of the Brief Core Schema Scale (BCSS), the emotional and cognitive components on the Brooding Scale (BS), the general trauma, emotional abuse, physical abuse, and sexual abuse on the Early Trauma Inventory Self Report-Short Form (ETI), and the Dietary Habits Questionnaire (DHQ) were significantly higher in patients compared to controls

Summary

Introduction

Childhood trauma (ChT) is a risk factor for psychosis. Negative lifestyle factors such as rumination, negative schemas, and poor diet and exercise are common in psychosis. Networks were constructed using 12 nodes from five scales: the Brief Core Schema Scale (BCSS), Brooding Scale (BS), Dietary Habits Questionnaire, Physical Activity Rating, and Early Trauma Inventory Self Report-Short Form (ETI). The emotional abuse was a mediator in the shortest pathway connecting the ETI and negative lifestyle for both groups. The negative others and negative self of the BCSS mediated emotional abuse to other BCSS or BS for patients and controls, respectively. Our findings suggest that rumination and emotional abuse were central symptoms in both groups and that negative others and negative self played important mediating roles for patients and controls, respectively

Methods

Results

Conclusion