Abstract
Metastasis is the process by which cancer cells acquire the capability to leave the primary tumor and travel to distant sites. Recent experiments have suggested that the epithelial–mesenchymal transition can regulate invasion and metastasis. Another possible scenario is the collective motion of cells. Recent studies have also proposed a jamming–unjamming transition for epithelial cells based on physical forces. Here, we assume that there exists a short-range chemical attraction between cancer cells and employ the Brownian dynamics to simulate tumor growth. Applying the network analysis, we suggest three possible phases for a given tumor and study the transition between these phases by adjusting the attraction strength.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
