Nested Variant of Transitional Cell Carcinoma with Hydronephrosis

Abstract

Won Seok Jang, Moon Sic Kwon, Sung Yul Park, Jin Seon Cho From the Department of Urology, Hallym University College of Medicine, Chuncheon, Korea The nested variant of transitional cell carcinoma (TCC) is rarely found in the bladder. Only about 80 such cases have been reported in the literature. Irregular nests and tubules of TCC infiltrating the lamina propria, with no involvement of the mucosal layer, characterize this disease. These characteristics make it difficult to diagnose the nested variant of transitional cell carcinoma. In this study we reported on a new case and review the relevant literature. This case was accompanied with hydronephrosis. We report on this case with its accompanying hydronephrosis because of its rarity and unusual histology, and also its prognostic significance emphasizes the need to distinguish it from classic TCC. (Korean J Urol 2007;48: 754-756) 󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏󰠏