Abstract
Background: Systolic dysfunction in heart failure (HF) predicts increased rates of morbidity and mortality. Nesiritide (NES) has been used for the acute treatment of HF. The safety, tolerability, and clinical effects of serial outpatient infusions of NES were recently evaluated in the FUSION study. This analysis examines the effect of NES on myocardial performance in patients (pts) within the FUSION trial with a baseline ejection fraction (EF) ≤40%.
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