Abstract

Background: Electrodiagnostic study is performed in a neurophysiology lab diagnosed peripheral neuropathy. Effect of ageing on nerve and muscle inform of muscle contractility decreased, change in the metabolism of muscle and neuromuscular junction transmission and reduced nerve conduction velocity. As the ageing population increases, information regarding the course of normal ageing, its impact on the nervous system, ways to maintain wellness, and disease that impact the elderly and their management is necessary. Therefore, this proposed study aims to elucidate the effect of physiological factors (height, Body Mass Index and gender) on nerve conduction study and find out the normative data for healthy elderly subjects in central India.
 Objectives:
 1) To establish normative data of nerve conduction study in Ulnar, median Tibial, and Peroneal nerves in normal healthy elderly subjects.
 2) To find out the effect of height, body mass index and gender on nerve conduction in healthy elderly subjects.
 Methodology: This will be a Cross-sectional study with participants aged > 60 years of both healthy subjects will be included in the study. The procedure will be performed after written consent from all the subjects. A normative data consist of parameters as distal motor Latency, peak to peak Amplitude and conduction velocity in motor nerve; peak to peak amplitude and nerve conduction velocity for sensory nerves. F wave minimum latency of motor nerve
 Nerve conduction study will be performed on Neuron Spectrum 5 (Neurosoft) machine. 
 Results: Normative data will compare with globally published literature.
 Conclusion: The study is expected to draw observation in relation to variables cited with the objectives, which will be compared to draw inference over normative data of nerve conduction studies in healthy elderly subjects from the Wardha district.

Highlights

  • Peripheral nerves are stimulated by adequate stimulation to nerve and record action potential [1]

  • The study is expected to draw observation in relation to variables cited with the objectives, which will be compared to draw inference over normative data of nerve conduction studies in healthy elderly subjects from the Wardha district

  • Null: - It is hypothesized that no variation exists for in healthy elderly subjects for nerve conduction study with gender, body mass index and height in central India population for latency, Amplitude, conduction velocity, F-minimum latency for motor nerve and Amplitude, conduction velocity for sensory nerve

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Summary

INTRODUCTION

Peripheral nerves are stimulated by adequate stimulation to nerve and record action potential [1]. Soudmand et al hypothesized that it is unlikely that the same would hold true for the arms [15] Physiologic factors such as temperature affect nerve conduction study inform nerve conduction velocity, distal latency, and Amplitude. Of physiological factors Gender, Height and BMI on nerve conduction velocity and find out normative data for healthy elderly subjects in central India. This study suggested the normative data in standard settings for the median or the ulnar nerves in healthy individuals [21]. Some studies evaluate the effect of Physiological factors height, age, BMI and effect of temperature nerve conduction velocity. Temperature affects nerve conduction velocity & India is a tropical region with a hot climate, there is a need to determine a range of normative values in this part of India [22]

Objectives
Hypothesis
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Statistical Analysis
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DISCUSSION AND CONCLUSION
Preston

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