Abstract
The study includes 150 children with primary nephrotic syndrome (NS), aged 16 months to 13 years with a median age of 5 years. The male to female ratio was 2:1 and the familial occurrence was 6%. Amongst 48 biopsied patients, 19 (39%) had focal segmental glomerulosclerosis, 17 (35%) had diffuse mesangial proliferative glomerulonephritis (MesPGN) and 10 (21%) had minimal change nephropathy. About 90% of patients responded to the initial prednisolone therapy. Subsequently 45% of steroid-sensitive patients had frequent relapses, 23% had no relapses, 21% had infrequent relapses and 5% became steroid resistant. Saudi children with primary NS showed no differences as regards age at onset, male predominance and response to initial prednisolone therapy when compared with published data from other countries. However, the higher incidence of familial occurrence, the relatively high frequency of MesPGN, the rarity of infection-related NS and a decreasing incidence of serious infections with improving socio-economic status were all noteworthy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
