Abstract
Kimura’s disease is characterized by benign subcutaneous masses located in the head and neck region, often accompanied by regional lymphadenopathy and salivary gland involvement. It is a rare disease that predominantly occurs in young Asian males. Histological analysis shows follicular hyperplasia with eosinophilic infiltration; blood examination usually reveals eosinophilia and elevated concentrations of immunoglobulin E (IgE). The aetiology is still unclear; autoimmune diseases, chronic infections and delayed hypersensitivity reactions are considered as possible causes. Renal involvement including nephrotic syndrome is common [1]. We report an African-Caribbean male who developed nephrotic syndrome due to glomerular tip lesions following uncomplicated surgery for a relapsing left-sided mandibular tumour that was diagnosed as Kimura’s disease.
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