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Abstract
Galle Medical Journal, Vol 18: No. 1, March 2013, Page 54-56 DOI: http://dx.doi.org/10.4038/gmj.v18i1.5509
Highlights
Kidney is the mostly affected visceral organ in systemic lupus (SLE)
Lupus nephritis typically occurs in patients aged 20-40 years [6]
More than 50% of the cases of lupus nephritis belong to ISN / RPS class III and IV
Summary
Kidney is the mostly affected visceral organ in systemic lupus (SLE). Renal involvement is seen in 40- 85 % of patients with SLE [1]. The International Society of Nephrology and Renal Pathology (ISN/RPS) classifies Lupus nephritis into six classes (I - VI). Patients with mesangial proliferative lupus nephritis (MPLN - ISN/RPS class II) are supposed to have a benign course with mild degree of proteinuria and intact renal function. Nephrotic range proteinuria is typically seen with lupus nephritis ISN/RPS class V and with class III and IV [2]. There are few reported cases in literature where nephrotic syndrome was associated with MPLN [3,4]. We report a young girl presented with nephrotic syndrome and detected to have SLE with MPLN after investigations
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