Abstract
NEPHROTIC SYNDROME is a common complication of diabetic nephropathy that usually develops after a long period of gradually worsening proteinuria and frequently progresses to end-stage renal disease. The characteristic pathologic findings in diabetic nephropathy are diffuse or nodular mesangial sclerosis and glomerular basement membrane (GBM) thickening, accompanied by chronic tubular atrophy, interstitial fibrosis, and prominent arteriosclerosis.1 Other glomerular diseases, superimposed on or unrelated to diabetic glomerulosclerosis, are not uncommon in patients with type 2 diabetes mellitus undergoing renal biopsy and have important implications for therapy and prognosis.
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