Abstract
Nephropathy and a syndrome of edema were produced in miniature swine by cultures of Penicillium viridicatum grown on autoclaved corn. The dried and ground cultures were mixed at a 50% concentration with a commercial pig feed. After a few days of feeding, the pigs became depressed, developed anorexia, posterior paresis, elevated blood urea nitrogen levels, proteinuria, and glycosuria. Gross lesions included subcutaneous edema, ascites, hydrothorax, hydropericardium, and mesenteric edema. Perirenal edema with accumulation of variable amounts of bloody fluid between renal capsule and parenchyma was a remarkable feature of the toxicosis. Microscopic lesions included edema of various tissues and degenerative changes in the kidney.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.