Abstract
Objective: The purpose of this manuscript is to review various clinical and neuroimaging features of vascular pathology in the fetus and neonate.Methods: A PubMed search of literature from 1978 to 2007 was performed using key search terms. Scientific papers pertinent to fetal and neonatal strokes were included and analysed.Results: The analysis of the multiple causes of fetal and neonatal vascular compromise including maternal, placental, infectious, metabolic/prothrombotic, traumatic and cardiac factors, current therapy and outcome data, is presented and discussed throughout the length of the paper.Conclusion: With increasing vigilance among physicians and improved neuroimaging modalities, the diagnosis of neonatal stroke is now made earlier, with increasing frequency and greater accuracy.
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