Neonatal Sepsis: Haematological Perspectives

Abstract

Neonatal sepsis (NS) is a leading cause of neonatal morbidity and mortality and is considered a global public health challenge. The organisms and pathogens most commonly associated with neonatal sepsis vary by country. Pathogens range from Gram-positive and Gramnegative bacteria to viruses and fungi, with bacteria being the most commonly identified. Bacteria most commonly involved include Staphylococcus aureus, coagulase-negative staphylococci (CONS), Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, and Group B Streptococcus increase, or urine culture is usually delayed for a day or two. A battery of tests, including C-reactive protein, total leukocyte count, absolute neutrophil count, platelet count, neutrophil cytoplasmic vacuolization, and polymorphic gastric aspiration cytology, was performed in neonates with a clinical diagnosis of NS. It's an excellent screening test. Keywords: Sepsis, neonates, haematological parameters, laboratory diagnosis, clinical findings