Abstract

Neonatal seizures occur frequently in fullterm and preterm infants, particularly in those suffering from pre-, peri-, or neonatal problems affecting the developing brain, e.g. hypoxic-ischemic encephalopathy, metabolic disorders, infectious diseases, and cerebral malformations, especially migrational disorders resulting in various types of cortical dysgenesis. Neonatal seizures without underlying diseases may occur as benign (often familial) neonatal seizures which are due to genetically determined defects of ion channels, predominantly the potassium channel.

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