Abstract
Neonatal appendicitis is a rare clinical entity associated with remarkable morbidity and mortality. Appendicular perforation is common and the diagnosis is usually made intra-operatively. The causative etiology of neonatal perforated appendicitis (NPA) is a subject of debate and has not been elucidated. Although many etiologic theories exist, increasing evidence suggests a subset of NPA cases may represent a form of necrotizing enterocolitis (NEC) localized to the appendix. We herein present a review of the current literature to include cases of NPA attributed to localized NEC. A high index of clinical suspicion and early laparotomy are recommended.
Highlights
Neonatal appendicitis is exceedingly rare with an incidence of approximately 40 per 100,000 live births [1,2]
We present a review of current literature involving a subset of reported Neonatal perforated appendicitis (NPA) cases where localized necrotizing enterocolitis (NEC) of the appendix was thought to be a causative etiology
Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix the neonatal appendix less prone to intraluminal obstruction than their older counterparts [4,5,7]
Summary
Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review. John Matthew Williams, Adrianne Myers-Webb, Ramesh Krishnan, James W Eubanks III1*. How to cite: Tumen A, Chotai PN, Williams JM, Myers-Webb A, Krishnan R, Eubanks III JW. Neonatal perforated appendicitis attributed to localized necrotizing enterocolitis of the appendix: A review.
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