Abstract
ABSTRACT Total body water in per cent of body weight at birth and at the time of maximum neonatal weight loss (generally 4 or 5 days after birth) is on the average practically unchanged in normal, full-term infants. Infants born to diabetic mothers exhibit a minor, but not significant decrease. This finding does not support the assumption that diab. infants utilize their fat depots to any marked extent to cover their energy requirement during the first few days of life in which they are often starved and that the large water excretion is due to the burning of fat. It agrees, however, with their high protein metabolism (reflected by the high urinary excretion of nitrogen). The reason why fat is not mobilized is discussed, and it is suggested that hyperinsulinism may be present.
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