Abstract

BL Chawes, P Poorisrisak, SL Johnston, H Bisgaard. J Allergy Clin Immunol. 2012;130(2):354–361, e3 To determine if host factors in neonates expressed as bronchial hyperresponsiveness precede later development of acute severe bronchiolitis. Previous studies showed that abnormal neonatal pulmonary function was associated with asthma by age 7 years. This study was nested in the Copenhagen Prospective Studies on Asthma in Childhood, a prospective study of a birth cohort of 411 neonates born to mothers with a history of asthma. Infants were enrolled at 1 month of age. Exclusion criteria included symptoms of lower …

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