Abstract
Purpose: Airway pressure release ventilation (APRV) is a relatively new mode of ventilation in neonates, that is able to achieve high mean airway pressures (MPaw) with lower peak pressures as compared to conventional synchronized intermittent mandatory ventilation (SIMV). It has also been associated with a favorable hemodynamic profile and improved patient comfort. Our hypothesis is that APRV is comparable in survival rates to high frequency oscillatory ventilation (HFOV) as a rescue mode of ventilation in neonates that fail SIMV. …
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