Abstract
Salts of lithium, present in the human diet at trace levels,1 are used to manage depressive, manic and psychotic symptoms in bipolar disorder and related conditions.2, 3 Although a neurological function for lithium was first proposed over 60 years ago based on its anti-manic properties,2 surprisingly, a significant pool of lithium has never been identified in the brain.4, 5 In this study, with quadrupole inductively coupled plasma-mass spectroscopy, lithium is identified as a physiological trace element in the human neocortex. Moreover, cortical levels of lithium are found to be elevated in bipolar subjects with no past history of lithium pharmacotherapy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
