Abstract

Cleavage reaction of nuciferine (VII) with metallic sodium in liquid ammonia was carried out and it was found that the methoxyl group in 1-position is liberated to form 2-methoxy-aporphine (VIII) which was identified with the specimen synthesized by another route. The same reaction of nornuciferine (IX) also resulted in the liberation of methoxyl in 1-position to form 2-hydroxyaporphine (X) but another substance (XI) was also obtained at the same time which seemed to have been formed by further progress of the reaction.

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