Abstract
BackgroundPublishing negative seroprevalence studies not only helps to have more accurate seroprevalence estimates but also allows calculating the specificity of the diagnostic tests used. We performed a population-based Trypanosoma cruzi seroprevalence survey in a community in central Mexico.ResultsWe surveyed 204 women and children and collected blood by finger prick. We performed rapid tests (Stat-Pak, Chembio, Inc., Medford, New York) and recombinant Chagas ELISA tests v3.0 (Wiener, Rosario, Argentina). All rapid tests and all ELISA tests were negative.ConclusionThe rapid test had 100 % of specificity compared to the ELISA.
Highlights
Publishing negative seroprevalence studies helps to have more accurate seroprevalence estimates and allows calculating the specificity of the diagnostic tests used
The results of the test under evaluation need to be compared to a gold standard: at least two tests need to be performed on each sample to calculate specificity
*Correspondence: padillawarm@gmail.com 1 División de Ciencias de la Salud e Ingenierías, Departamento de Enfermería y Obstetricia, Campus Celaya Salvatierra Universidad de Guanajuato, México Mutualismo 303, CP38060 Celaya, Gto, Mexico Full list of author information is available at the end of the article countries in Latin America
Summary
Publishing negative seroprevalence studies helps to have more accurate seroprevalence estimates and allows calculating the specificity of the diagnostic tests used. Publishing such negative studies helps to have more accurate seroprevalence estimates and allows calculating the specificity of the diagnostic tests used. *Correspondence: padillawarm@gmail.com 1 División de Ciencias de la Salud e Ingenierías, Departamento de Enfermería y Obstetricia, Campus Celaya Salvatierra Universidad de Guanajuato, México Mutualismo 303, CP38060 Celaya, Gto, Mexico Full list of author information is available at the end of the article countries in Latin America.
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