Abstract

Pressure ulcers are a highly prevalent source of morbidity with an equally high incidence of up to 38.0\% amongst different categories of healthcare institutions. Therefore, the management and therapeutic approach toward these often hospital- or facility-acquired problems remain critical aspects of long-term care. Negative pressure wound therapy (NPWT) has proven effective in addressing the barriers to pressure ulcer healing including increasing blood flow to previously ischemic wound areas by generating subatmospheric pressure which vacuums in circulation. The objective of this study was to compare negative pressure wound therapy (NPWT) versus surgical wounds healing by secondary intention (SWHSI). A systematic literature search was conducted using the PubMed and Scopus search engine up until the 20 Th January 2017 including the terms: “negative pressure wound therapy” and “pressure ulcers”. In this systematic review, six randomized controlled trials were included. NPWT is deemed appropriate and effective method and widely used by clinicians to promote the healing of wounds and ulcers of different etiology. The heterogeneity found in individual trials regarding the inclusion criteria, therapeutic procedures, the criteria and methods of outcome evaluation, however, did not allow for a data evaluation with statistically valid conclusions. It is reasonable to assume that their subset of patients with pressure ulcers that can be effectively treated with NPWT, with optimal results and good cost-benefit ratio, also with respect to the quality of life.

Highlights

  • P RESSURE ulcers are a significant source of morbidity with an high incidence of up to 38.0% amongst different categories of healthcare institutions.[1, 2] In particular this condition affects people aged over 65 years with a prevalence ranging from 0.3% to 46% and an incidence ranging from 0.8% to 34%.3 the management and therapeutic approach toward these often hospital- or facilityacquired problems remain critical aspects of long-term care.[4]

  • negative pressure wound therapy (NPWT) is deemed appropriate and effective method and widely used by clinicians to promote the healing of wounds and ulcers of various etiology

  • This would seem to indicate that the NPWT should not be used too early in pressure ulcers

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Summary

Introduction

P RESSURE ulcers are a significant source of morbidity with an high incidence of up to 38.0% amongst different categories of healthcare institutions.[1, 2] In particular this condition affects people aged over 65 years with a prevalence ranging from 0.3% to 46% and an incidence ranging from 0.8% to 34%.3 the management and therapeutic approach toward these often hospital- or facilityacquired problems remain critical aspects of long-term care.[4]. P RESSURE ulcers are a significant source of morbidity with an high incidence of up to 38.0% amongst different categories of healthcare institutions.[1, 2] In particular this condition affects people aged over 65 years with a prevalence ranging from 0.3% to 46% and an incidence ranging from 0.8% to 34%.3. The management and therapeutic approach toward these often hospital- or facilityacquired problems remain critical aspects of long-term care.[4] Often, complexities exist structurally within these wounds. The objective of this study was to compare negative pressure wound therapy (NPWT) versus surgical wounds healing by secondary intention (SWHSI). B. Types of studies Randomized controlled trials (RCTs) were identified through a systematic review of published literature (full article, thesis, or abstract)

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