Abstract
BackgroundThis meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery.MethodsA systematic search was performed in PubMed, Embase, and the Cochrane Library databases. The outcome measures included deep surgical site infection (SSI), superficial SSI; wound dehiscence and length of hospital stay. Cochrane collaboration’s tool and the Newcastle–Ottawa Scale (NOS) were used to evaluate literature qualities. Meta-analysis was performed using RevMan 5.3 software.ResultsA total of 6 studies including 2 randomized controlled trials (RCTs) and 4 cohort studies met our inclusion criteria. NPWT resulted in a significantly lower incidence of deep SSI, superficial SSI, and wound dehiscence than conventional wound dressings. However, no statistically significant difference was found in the length of hospital stay.ConclusionsNPWT appeared to be an efficient alternative to help prevent SSIs and wound dehiscence on closed incisions in orthopedic trauma surgery. Rational use of NWPT should be based on the presence of patient’s condition and risk factors.
Highlights
This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery
Inclusion and exclusion criteria We identified literature that met the following inclusion criteria: (1) clinical studies comparing NPWT versus conventional wound dressings for closed incisions in orthopedic trauma surgery, including randomized control trials (RCTs), cohort studies, and case-control studies; (2) published in English; (3) outcomes including the incidence of surgical site infection (SSI); and (4) full text of studies available
Manual searching of relevant references did not add additional studies
Summary
This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery. Wound complications within the realm of orthopedic trauma surgery are a major concern. Wound healing is challenging following high-energy trauma, and frequently contribute to postoperative wound dehiscence and surgical site infections (SSIs) [1, 2]. NPWT has 3 main components that create a negative pressure environment: a vacuum device, a porous dressing, and a connector that allows communication. The wound and porous dressing are sealed via an occlusive adhesive dressing, and communicate with the vacuum device via a connector creating a subatmospheric pressure environment. NPWT promotes wound healing by providing wound coverage, reducing dead space and minimizing tension, Wang et al Journal of Orthopaedic Surgery and Research (2019) 14:427
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