Abstract

Background: Negative Pressure Pulmonary Edema (NPPE) is an uncommon, but well recognized clinical entity that continues to be reported as a complication of upper airway obstructions during induction or emergence. It results from the negative intrathoracic pressure generated with spontaneous ventilation with concurrent upper airway obstruction. Aim: To present an unusual case of NPPE and review the pathophysiology and treatment. Case: It usually occurs in young healthy athletic adults. We are reporting NPPE in a nine-month-old ex-premature baby. We discuss his intraoperative events leading to NPPE, subsequent intraoperative course and treatment. Conclusion: NPPE needs to be promptly recognized and treated. If the edema resolves, the patient can be successfully extubated, but should be observed overnight.

Highlights

  • Negative Pressure Pulmonary Edema (NPPE) is an uncommon complication that can occur during induction of anesthesia, but usually occurs during emergence after extubation

  • NPPE is an uncommon complication, it is still a well recognized clinical entity that results from the negative intrathoracic pressure generated with spontaneous ventilation with concurrent upper airway obstruction [1]

  • NPPE develops after the relief of acute upper airway obstruction caused by epiglottitis, tumors, obesity, hiccups, obstructive sleep apnea, or mediastinal masses [2]

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Summary

Introduction

Negative Pressure Pulmonary Edema (NPPE) is an uncommon complication that can occur during induction of anesthesia, but usually occurs during emergence after extubation. NPPE is an uncommon complication, it is still a well recognized clinical entity that results from the negative intrathoracic pressure generated with spontaneous ventilation with concurrent upper airway obstruction [1]. NPPE develops after the relief of acute upper airway obstruction caused by epiglottitis, tumors, obesity, hiccups, obstructive sleep apnea, or mediastinal masses [2]. It can be caused by laryngospasm during induction or following extubation. (2015) Negative Pressure Pulmonary Edema on Extubation of a 9-Month-Old Baby Boy. Open Journal of Anesthesiology, 5, 93-95. Our aim is to briefly review the pathophysiology and our treatment of NPPE

Case Report
Intraoperative
Postoperative Course
Discussion
Conclusion

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