Negative-Pressure Cavitation Extraction of Secoisolariciresinol Diglycoside from Flaxseed Cakes.

Hao Tian,Wan-Yi Li,Jian-Wen Wang,Zhi-Min Li,Dan Xiao

doi:10.3390/molecules200611076

Abstract

The negative-pressure cavitation extraction (NPCE) technique was applied firstly to extract secoisolariciresinol diglucoside (SDG) from flaxseed cakes. The significant extraction parameters were screened by fractional factorial design (FFD). The optimal parameters were determined using the central composite design (CCD) with the two variables, NaOH amount and the liquid/solid ratio. The conditions of the extraction were optimized by using response surface methodology (RSM). Under the optimal conditions, the extraction yield and the extraction purity of SDG was 16.25 mg/g and 3.86%, respectively. The efficiency of NPCE was compared with that of conventional extraction methods. Our results demonstrated that NPCE was comparable to the well-known ultrasound-assisted extraction in term of extraction yield and purity. This extraction technique has advantages of less time-consuming, low solvent usage and high throughput capability.

Highlights

Flax (Linum usitatissimum L.) is an economically important oilseed and fiber crop
Significant Parameters Screened by Fractional Factorial Design (FFD)
The results indicated the experimental values were in good agreement with the predicted ones, suggesting the reliable response surface methodology (RSM) models used in negative-pressure cavitation extraction (NPCE)

Summary

Introduction

Flax (Linum usitatissimum L.) is an economically important oilseed and fiber crop. Traditionally, flaxseed oil (40%–45%, w/w) has been used mostly for industrial purposes in the manufacture of paints, varnishes, soaps and printer inks [1]. Flaxseed oil rich in α-linolenic acid has been marketed as a health food to minimize disease risks associated with hyperlipidemia, mammary cancer and atherosclerosis [2,3,4]. After the oil is extracted from the seed, the flaxseed cake is used usually for livestock feed as a by-product. The concern about environmentally friendly, selective, and effective techniques for lignan extraction from flaxseed has gained in interest. Among these techniques, microwaves, enzyme (β-glucuronidase/sulfatase or cellulase) aided extraction and electrotechnologies such as high voltage electrical discharge and pulsed electric fields have shown their efficiencies for SDG extraction from flaxseed [15,16,17,18,19]

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