Abstract

Negative myoclonus refers to an abrupt involuntary movement caused by sudden, brief interruptions of muscle activity. Recently, the Task Force on Classification and Terminology of the International League against Epilepsy recognized negative myoclonus as a seizure type, defining it as an “interruption of tonic muscle activity for less than 500 ms without evidence of preceding myoclonia.” Clinically, negative myoclonus is classified into four types: asterixis, postural lapses, epileptic negative myoclonus, and physiologic negative myoclonus. Asterixis, which usually occurs in metabolic or toxic encephalopathies, is considered to be subcortical in origin but the cerebral cortex may be involved in some cases.KeywordsNegative MyoclonusTonic Muscle ActivityToxic EncephalopathyAsterixSeizure TypeThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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