Abstract
To study the stability and predictive significance of positive and negative syndromes, we assessed a group of young acute schizophrenics at index admission (N = 37) and upon 2-year follow-up (N = 19). We found these syndromes longitudinally unstable, though equally prevalent in both phases. The baseline negative score was predictive of favorable outcome. The prognostic value of negative symptoms was independent of premorbid ratings, and, in combination these predictors, correlated strongly with follow-up level of functioning. The relationship between negative syndrome and outcome was partly explained by depression, which correlated significantly with baseline negative score. Theoretical and clinical implications of this overlay of a negative syndrome with depression in young acute schizophrenics are presented.
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