Abstract

A 51-year-old Hispanic woman was referred to The University of Texas M. D. Anderson Cancer Center with a 5-year history of dyspnea, coughing, wheezing, mediastinal widening, and a mass in the right upper lobe of the lung. A small cell lymphocytic lymphoma producing an extensive necrotizing granulomatosis reaction was diagnosed during her workup. Ten months later, the patient developed a severe obstructive respiratory syndrome, and died of respiratory insufficiency. This appears to be a case of necrotizing sarcoid granulomatosis causing a malignant airway obstruction. Abbreviations: BAL=Bronchoalveolar lavage NSG=Necrotizing sarcoid granulomatosis RUL=Right upper lobe

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