Abstract
We modified the elastase-induced aneurysm model by use of a simple surgical technique in rabbits. A temporary arcuated aneurysm clip was placed at the origin of the right common carotid artery (RCCA), ascertaining the inner edge of the clip blade on the juncture of the RCCA and right subclavian artery (RSCA), and the elastase-induced aneurysm procedure was undertaken. We found elastase and location of the temporary arcuated aneurysm clip are critical to the success of this aneurysm model.
Highlights
The elastase-induced aneurysm model has been gradually accepted in recent years because it resembles a human aneurysm in hemodynamics and histology.[1,2]
Hoh et al[4] reported a new modified technique to the elastase aneurysm model, in which the rabbit right common carotid artery (RCCA) origin was surgically exposed and temporarily occluded with an aneurysm clip and the tapped segment was infused with elastase
The arc of the temporary arcuate aneurysm clip partly protruded into the right subclavian artery (RSCA), and the tip of the integrated catheter approached the clip, which ensured that the neck of aneurysm was digested sufficiently by elastase
Summary
SUMMARY: We modified the elastase-induced aneurysm model by use of a simple surgical technique in rabbits. A temporary arcuated aneurysm clip was placed at the origin of the right common carotid artery (RCCA), ascertaining the inner edge of the clip blade on the juncture of the RCCA and right subclavian artery (RSCA), and the elastase-induced aneurysm procedure was undertaken. We found elastase and location of the temporary arcuated aneurysm clip are critical to the success of this aneurysm model
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