Neck circumference as a new anthropometric indicator for prediction of insulin resistance and components of metabolic syndrome in adolescents: Brazilian Metabolic Syndrome Study.

Cleliani De Cassia Da Silva,Ana Carolina J Vasques,Maria Ângela R De G M Antonio Antonio,Ana Maria De B Rodrigues,Bruno Geloneze,Daniella Fernandes Camilo,Mariana Porto Zambon,Roberta Soares L Cassani

doi:10.1590/0103-0582201432210713

Cleliani De Cassia Da Silva, Ana Carolina J Vasques + Show 6 more

Open Access

https://doi.org/10.1590/0103-0582201432210713

Copy DOI

Abstract

OBJECTIVE: To evaluate the correlation between neck circumference and insulin resistance and components of metabolic syndrome in adolescents with different adiposity levels and pubertal stages, as well as to determine the usefulness of neck circumference to predict insulin resistance in adolescents. METHODS:Cross-sectional study with 388 adolescents of both genders from ten to 19 years old. The adolescents underwent anthropometric and body composition assessment, including neck and waist circumferences, and biochemical evaluation. The pubertal stage was obtained by self-assessment, and the blood pressure, by auscultation. Insulin resistance was evaluated by the Homeostasis Model Assessment-Insulin Resistance. The correlation between two variables was evaluated by partial correlation coefficient adjusted for the percentage of body fat and pubertal stage. The performance of neck circumference to identify insulin resistance was tested by Receiver Operating Characteristic Curve. RESULTS: After the adjustment for percentage body fat and pubertal stage, neck circumference correlated with waist circumference, blood pressure, triglycerides and markers of insulin resistance in both genders. CONCLUSIONS: The results showed that the neck circumference is a useful tool for the detection of insulin resistance and changes in the indicators of metabolic syndrome in adolescents. The easiness of application and low cost of this measure may allow its use in Public Health services.

Highlights

Body composition and body fat distribution are associated with complications such as insulin resistance (IR), dyslipidemia, diabetes mellitus type 2, and cardiovascular diseases (CVD) in adults, children, and adolescents[1,2]
waist circumference (WC) has been used in the diagnosis of metabolic syndrome (MS), as a predictor of IR, and in the assessment of risk factors for CVD in adolescents[4]
Mean BF%, glycemia, total cholesterol (TC), LDL, and median HbA1C and AST were higher in prepubertal males, with a statistically significant difference

Summary

Introduction

Body composition and body fat distribution are associated with complications such as insulin resistance (IR), dyslipidemia, diabetes mellitus type 2, and cardiovascular diseases (CVD) in adults, children, and adolescents[1,2]. BMI is currently the most common measurement for the diagnosis of overweight and obesity in children and adolescents It cannot always assess people’s individual risks of endocrine and metabolic complications, since it does not evaluate body fat distribution[3]. There are limitations for this age group, such as the lack of a standard method of measurement[5,6,7]; lack of an international standard due to ethnic variation; lack of a cutoff point for cardiovascular and metabolic risks; and practical obstacles, such as the need to undress, during winter. This may have a psychological effect on this age group[8]

Methods

Results

Discussion

Conclusion