Nebulized hypertonic saline for acute bronchiolitis?

Abstract

In recent years, hypertonic saline has gained popularity for the treatment of acute bronchiolitis in infancy, often being administered in the emergency department. In this issue of The Journal, Al-Ansari et al report a randomized controlled trial of 5%, 3%, and 0.9% saline for this condition. The response seemed to be better with 5% hypertonic saline compared with other concentrations, and it was safe and well-tolerated. This is a small, preliminary study that should be repeated as a multi-center study with a larger sample size to confirm the findings. In recent years, hypertonic saline has gained popularity for the treatment of acute bronchiolitis in infancy, often being administered in the emergency department. In this issue of The Journal, Al-Ansari et al report a randomized controlled trial of 5%, 3%, and 0.9% saline for this condition. The response seemed to be better with 5% hypertonic saline compared with other concentrations, and it was safe and well-tolerated. This is a small, preliminary study that should be repeated as a multi-center study with a larger sample size to confirm the findings. Nebulized 5% or 3% Hypertonic or 0.9% Saline for Treating Acute Bronchiolitis in InfantsThe Journal of PediatricsVol. 157Issue 4PreviewTo compare the efficacy and safety of 5%, 3%, and 0.9% saline solution for treating acute bronchiolitis in the prehospital setting. Full-Text PDF