Abstract
Juvenile idiopathic arthritis (JIA) is an exclusion diagnosis that encompasses all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. In the ILAR classification, this heterogeneous group of chronic arthritides has been categorized on clinical and laboratory grounds to try to identify homogeneous, mutually exclusive categories suitable for etiopathogenic studies. However, the ILAR classification is complex and includes several inclusion and exclusion criteria. As a result, the correct placement of a patient in a specific category is not simple.
Highlights
Juvenile idiopathic arthritis (JIA) is an exclusion diagnosis that encompasses all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin
Most problems were related to the lack of 2 determinations of rheumatoid factor (RF) at least 3 months apart, the missing data in the indication of the presence or absence of psoriasis in the patient or in the presence or absence of a history of psoriasis in a first degree relative, the lack of assessment of HLA-B27 antigen, or the discrepancies in data results in the indication of a family history of spondyloarthropathies
In current clinical practice nearly 20% of JIA patient were categorized according to physician diagnosis attribution despite the lack of fulfillment of the ILAR exclusion criteria
Summary
Juvenile idiopathic arthritis (JIA) is an exclusion diagnosis that encompasses all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. In the ILAR classification, this heterogeneous group of chronic arthritides has been categorized on clinical and laboratory grounds to try to identify homogeneous, mutually exclusive categories suitable for etiopathogenic studies. The ILAR classification is complex and includes several inclusion and exclusion criteria. The correct placement of a patient in a specific category is not simple
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