Abstract
Near Infrared Spectroscopy alike Magnetic Resonance Imaging: Complementary Data in Rat Brain after Cocaine Treatment
Highlights
Near Infrared Spectroscopy (NIRS)In 1977, Franz Jöbsis first introduced near infrared spectroscopy (NIRS) for the in vivo monitoring of tissue oxygenation [1]
Positive evidence will further confirm the utility of such prototype for real time translational rodent-man in vivo non invasive studies
This was followed by any significant changes of the NIRS parameters and 2 min later pure O2 is again supplied per os during 1 min
Summary
NIRSIn 1977, Franz Jöbsis first introduced near infrared spectroscopy (NIRS) for the in vivo monitoring of tissue oxygenation [1]. Thanks to its penetration depth and high temporal resolution and biochemical specificity NIRS is becoming a widely used research non-invasive instrument to measure tissue oxygen (O2) status and can be applied to biomedical research and clinical environments to measure oxygenation in a variety of tissues including muscle, brain and connective tissue. More recently it has been used in the clinical setting to assess circulatory and metabolic abnormalities.
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