Abstract

We report a reliable and facile procedure to prepare near infrared fluorescence (NIRF)-magnetic resonance dual-modal imaging probes (DMIPs) using Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles. High intensity NIRF and a relaxation rate (17.7 mM−1s−1) can be observed. Furthermore, the DMIPs in saline were injected into mice through the tail vein for imaging.

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