Abstract

ABSTRACTHere, we report the nearly complete genome sequences of nine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with the D614G mutation. These viruses were detected from various infected individuals with different levels of severity from Pahang, Malaysia. In addition, this study described the presence of lineage B.1.351 as a type of variant of concern (VOC) and lineages B.1.466.2 and B.1.524 as local variants.

Highlights

  • The current pandemic of coronavirus disease 19 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the viral family Coronaviridae and genus Betacoronavirus (1)

  • The constructed library was sequenced on an iSeq 100 sequencing system (Illumina, Inc., USA) with run configuration of 1 Â 300 bp or 1 Â 250 bp

  • 125,319 single-end reads were generated from each sample

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Summary

Introduction

The current pandemic of coronavirus disease 19 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the viral family Coronaviridae and genus Betacoronavirus (1). Sequence name hCoV-19/Malaysia/UMP-IIUM5480/2021 hCoV-19/Malaysia/IIUM5556/2021 hCoV-19/Malaysia/IIUM5676/2021 hCoV-19/Malaysia/IIUM5754/2021 hCoV-19/Malaysia/IIUM5755/2021 hCoV-19/Malaysia/IIUM5763/2021 hCoV-19/Malaysia/IIUM5770/2021 hCoV-19/Malaysia/IIUM6472/2021 hCoV-19/Malaysia/IIUM91/2020 B.1.351 Beta (b) B.1.351 Beta (b) B.1.524 No WHO label; Malaysian lineagea B.1.351 Beta (b) B.1.351 Beta (b) B.1.466.2 No WHO label; Indonesian lineagea B.1.351 Beta (b) B.1.351 Beta (b) B.1.468 No WHO label; Indonesia/Singapore lineagea

Results
Conclusion

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