Abstract
Coxsackievirus group A (CV-A) strains are important pathogens of hand, foot, and mouth disease and herpangina. We report here the near-complete genome sequences of 12 CV-A strains isolated from infants and children with different clinical diseases. The presented data will be very useful for future genome-based epidemiological studies.
Highlights
Coxsackievirus group A (CV-A) strains are important pathogens of hand, foot, and mouth disease and herpangina
Microbiology Resource Announcement phylogenetic tree constructed by using the program MEGA7.0.26 (11), based on the complete VP1 gene of the four Coxsackievirus A2 (CV-A2) strains of this study and CV-A2 reference strains retrieved from GenBank, indicated that the four CV-A2 strains of the study clustered to genogroup D according to the genotyping method proposed by Yang et al (12)
The three CV-A6 strains from this study show 3.5% to 7.4% nt differences and 0.9% to 1.7% aa differences from each other
Summary
Coxsackievirus group A (CV-A) strains are important pathogens of hand, foot, and mouth disease and herpangina. The four CV-A2 strains of this study show 1.2% to 3.6% nucleotide (nt) differences across the entire genome and 0.6% to 1.1% amino acid (aa) differences across the entire polyprotein. Received 13 December 2018 Accepted 21 January 2019 Published 21 February 2019 mra.asm.org 1
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