Nausea and vomiting in pregnancy \u2013 association with pelvic girdle pain during pregnancy and 4-6\xa0months post-partum

Arthur Chortatos,Marit B Veierød,Elisabeth Krefting Bjelland,Malin Eberhard-Gran,Per Ole Iversen,Margaretha Haugen

doi:10.1186/s12884-018-1764-7

Abstract

BackgroundTo better understand previous associations reported regarding nausea and vomiting in pregnancy (NVP) and pelvic girdle pain (PGP), an investigation into timing of symptom onset for NVP and PGP in pregnancy, as well as the association of NVP with PGP 4-6 months post-partum was performed. We hypothesised that women with NVP symptoms would be most susceptible to experiencing persistence of PGP post-partum.MethodsFifty two thousand six hundred seventy-eight pregnancies from the Norwegian Mother and Child Cohort Study were analysed regarding nausea, vomiting, pelvic girdle pain, and health outcome data collected from questionnaires answered between gestation weeks 15, 20, 30, and 6 months post-partum. Logistic regression was used.ResultsWomen experiencing NVP and PGP together (6.9%) were heaviest in the sample, youngest at menarche and had highest proportion with education ≤12 years. The primiparous women in this group had the lowest timespan from menarche to pregnancy. Women with nausea alone (NP) and NVP had higher odds of PGP 4-6 months post-partum (adjusted odds ratio, aOR = 2.14, 95% CI 1.70–2.71, and aOR = 2.83, 95% CI 2.25–3.57, respectively), compared to symptom-free women. NP/NVP symptoms appeared early in the first trimester, while PGP symptoms appeared later in pregnancy. Women with longer durations of nausea and/or vomiting had a higher proportion of PGP compared to shorter duration women.ConclusionsWomen with NP and NVP had increased odds of PGP 4-6 months post-partum, and women with a long duration of nausea and/or vomiting had a higher proportion of PGP than women with shorter duration, both during pregnancy and 4-6 months post-partum. This finding suggests a synergistic relationship between NP/NVP and PGP.

Highlights

To better understand previous associations reported regarding nausea and vomiting in pregnancy (NVP) and pelvic girdle pain (PGP), an investigation into timing of symptom onset for NVP and PGP in pregnancy, as well as the association of NVP with PGP 4-6 months post-partum was performed
We recently reported that women with Nausea alone (NP) and NVP had increased odds for experiencing PGP compared with symptom-free (SF) women [24]
Maternal and gestational history Women with PGP tended to be heavier and with a higher pre-pregnancy Body mass index (BMI) compared to those without PGP (Table 1), and the highest means were for NVP women with PGP

Summary

Introduction

To better understand previous associations reported regarding nausea and vomiting in pregnancy (NVP) and pelvic girdle pain (PGP), an investigation into timing of symptom onset for NVP and PGP in pregnancy, as well as the association of NVP with PGP 4-6 months post-partum was performed. Women with a young age, previous deliveries, those overweight or obese, with an early menarche, with. Approximately 10% of women with PGP during pregnancy continued to experience pain up to 18 months after delivery [16, 17]. Known risk factors for PGP are smoking during pregnancy, a high BMI, young maternal age, previous pregnancies, and early menarche [18,19,20,21,22,23]

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