Abstract
The aim of the present study was to evaluate retrospectively histopathologically-diagnosed lesions that were detected in the kidney after radical nephrectomy for a preoperative diagnosis of kidney cancer. The medical records of 83 patients (51 male, 32 female) were included. Preoperative staging was accomplished by various methods including physical examination, blood hemography and biochemistry, abdominal ultrasonography (US), chest x-ray, abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI). Totals of 70 patients underwent radical nephrectomy and 13 nephron sparing surgery. Of the 83 patients, 70 had malignant lesions (renal cell carcinoma, squamous cell carcinoma or other malignancies) 13 had a variety of benign lesions, the most frequently detected being oncoytoma (6), angiomyolipoma (3), xanthogranulamatous pyelonephritis (2), cortical cyst (1) and chronic pyelonephritic change (1). It was concluded that in spite of great technological developments regarding radiological imaging modalities such as US, CT and MRI, benign lesions might still be detected pathologically in patients who undergo radical nephrectomy with the preoperative diagnosis of renal cancer. But, all renal masses should be regarded as malignant and should be managed surgically otherwise proven benign.
Highlights
Renal cell carcinoma (RCC), the eighth most common malignancy affecting adults, accounts for between 3% and 4% solid tumors and approximately 85-90% of all parenchymal renal tumors
Aim: The aim of the present study was to evaluate retrospectively histopathologically-diagnosed lesions that were detected in the kidney after radical nephrectomy for a preoperative diagnosis of kidney cancer
Preoperative staging was accomplished by various methods including physical examination, blood hemography and biochemistry, abdominal ultrasonography (US), chest x-ray, abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI)
Summary
Renal cell carcinoma (RCC), the eighth most common malignancy affecting adults, accounts for between 3% and 4% solid tumors and approximately 85-90% of all parenchymal renal tumors. Most tumors present in the fifth to seventh decade of life, with a median age at diagnosis of 66 years and median age at death of 70 years. RCC is among the most common 15 malignancies occurring in both sex and the incidence has been continuously increasing since 1975 (Edwards et al, 2005). The most important reason for the increase in the incidence is the advances in imaging techniques and the common use of these techniques, which have surely resulted in considerable changes in the diagnostic and therapeutical strategies of the disease. In spite of all these advances in imaging techniques, it is not possible radiologically to differentiate between the benign-malign natures of all masses. In benign masses in particular, such as focal xanthogranulomatous pyelonephritis, oncocytoma, chronic pyelonephritis and angiomyolipoma, it is difficult to establish a definite diagnosis before surgery (Remzi et al, 2007)
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