Abstract

In this issue of Chem , Lumb and colleagues report on an effective and simple catalytic system of copper and diamine ligands for the bio-inspired and unified synthesis of 1,2-aminophenols through direct aerobic phenol-amine coupling. Using this method, they prepared a structurally diverse family of 1,2-aminophenols and their derived heterocycles, including immunosuppressive benzoxazoles and the indole alkaloid cephalandole A.

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