Abstract

The development of drug-resistant strains is rising and the search for new and novel ways of fighting new or reemerging microbes goes on. A hope of treating such multidrug-resistant infections came from plants mediated nanoparticles since nature is a generous source which provides a variety of chemical compounds that can be used for new drug discovery. Silver nanoparticles are reported to possess antiviral, antibacterial, antifungal, antiparasitic, larvicidal activity and anticancer properties. We reported green synthesis of silver nanoparticles mediated food plants Megaphrynium macrostachyum, Corchorus olitorus, Ricinodendron heudelotii, Gnetum bucholzianum, and Ipomoea batatas and their antibacterial efficacy against the Enterobacteriaceae Escherichia coli. The nature and size of the obtained nanoparticles are discussed as well as their Minimum Inhibitory Concentration (MIC) and the Minimum Bactericide Concentration (MBC) values considering their application in medical industry.

Highlights

  • Increasing resistance against antibiotics is a burning health problem and there is an urgent need to improve the existing drugs or find new, novel strategies to overcome this problem [1]

  • We describe the uses of the obtained silver nanoparticles as antimicrobial agent against Escherichia coli

  • The silver nanoparticles mediated leaves of Megaphrynium macrostachyum, Corchorus olitorus, Gnetum bucholzianum, and Ipomoea batatas and seed kernels of Ricinodendron heudelotii are obtained in the same synthetic conditions

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Summary

Introduction

Increasing resistance against antibiotics is a burning health problem and there is an urgent need to improve the existing drugs or find new, novel strategies to overcome this problem [1]. Nanoparticles, generally considered as particles with a size of up to 100 nm, exhibit completely new or improved properties as compared to the larger particles of the bulk material that they are made up of [2]. One of the most challenging goals in nanoparticle research is to develop successful protocols for the large-scale, simple, and (possibly) lowcost preparation of morphologically pure nanoparticles with identical properties. Nanoparticles should be stored and manipulated without losing their properties. Character ODC IND ADH βNAG LDC βGAL URE GLU LARL SAC GAT LAR 5KG DARL LIP αGLU

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