Abstract

Key words eukaryotic initiation factor 4A - rocaglamide - zotatifin - [3+2] cycloaddition - α-ketol rearrangement

Highlights

  • Natural products and traditional medicines are of great importance

  • It is emphasized on extraction, its isolation, and characterization of phytochemicals, which is a gift of nature in a rational and scientific way

  • Once the phytochemical is obtained, this can be used for further exploration through QSAR studies, molecular modeling, and animal studies followed by clinical trial

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Summary

Introduction

Natural products and traditional medicines are of great importance. Natural products and their derivatives have been recognized for many years as a source of therapeutic agents and structural diversity. The raw materials for Ayurvedic medicines were mostly obtained from plant sources in the form of crude drugs such as dried herbal powders or their extracts or mixture of products. Apart from these systems, there has been a rich heritage of ethnobotanical usage of herbs by various colorful tribal communities in the country [4]. Working role of every green herbal drugs from plant source and synthesis of bioactive products in their own way as God’s gift and preserve them within which are extractable and used raw material as and when required through various scientific process for various scientific investigations and study of herbal drug discovery.

Important steps for successful completion of natural drug discovery
Practical outlook of herbal drug discovery
Evaluation of plant extracts by judging of different biological test methods
Position of herbal drugs
Natural drugs available in market: anti-inflammatory
Ginger
Licorice root
Oregano
Future avenues in herbal drug discovery
Analytical methodologies
Phytochemical screening assay
Tests for carbohydrates
Tests for proteins
Tests for amino acids
Tests for steroid and triterpenoid
Tests for glycosides
Tests for flavonoids
Tests for alkaloids
Tests for tannins and phenolic compounds
Chromatography techniques
Methods of detection
Development of new technologies in natural drug discovery research
High-throughput screening
Findings
Conclusion
Full Text
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