Natural Product Chemistry of Gorgonian Corals of Genus Junceella⁻Part III.

Hsu-Ming Chung,Zhi-Hong Wen,Yi-Chen Wang,Chung-Chih Tseng,Lee-Shing Fang,Yang-Chang Wu,Tsong-Long Hwang,Nan-Fu Chen,Ping-Jyun Sung

doi:10.3390/md16090339

Abstract

The structures, names, bioactivities, and references of 82 natural products, including 48 new metabolites, purified from the gorgonian corals belonging to the genus Junceella are described in this review. All compounds mentioned in this review were obtained from Junceella fragilis, Junceella gemmacea, Junceella juncea, and Junceella sp., collected from tropical Indo-Pacific Ocean. Some of these compounds exhibited potential biomedical activities.

Highlights

IntroductionFollowing previous review reviewarticles articles focused marine-origin natural products, this reviewFollowing previous focused on on marine-origin natural products, this review covers covers the literature from October to August describes82 natural products (including the literature from October August2018,2018, and and describes from gorgonian corals belonging to the genusJunceella [1,2,3,4].new metabolites) from gorgonian corals belonging to the genus Junceella [1,2,3,4]
From gorgonian corals belonging to the genus new metabolites) from gorgonian corals belonging to the genus Junceella [1,2,3,4]
[5,6], this this review review provides provides structures, structures, names, names, bioactivities, andreferences references forcompounds all compounds including briaraneand norcembrane-type bioactivities, and for all including briarane- and norcembrane-type diterpenoids, diterpenoids, sterol, and Many nucleosides

Summary

Introduction

Following previous review reviewarticles articles focused marine-origin natural products, this review. 2018,2018, and and describes (including new metabolites) from gorgonian corals belonging to the genus. New metabolites) from gorgonian corals belonging to the genus Junceella (family Ellisellidae) [1,2,3,4]. [5,6], this this review review provides provides structures, structures, names, names, bioactivities, andreferences references forcompounds all compounds including briaraneand norcembrane-type bioactivities, and for all including briarane- and norcembrane-type diterpenoids, diterpenoids, sterol, and Many nucleosides. Many of these exhibited compounds exhibitedbioactivities interesting bioactivities in sterol, and nucleosides.

Junceella

Junceella Gemmacea

Junceella Juncea

Structures

Structures of juncenolides

3.3.Conclusions